By Lois Zoppi, BAJun 25 2019Researchers from the University of Southern California (USC) at the annual meeting of the American Society for Microbiology have revealed that plant foods may be transmitting antibiotic resistance to the gut microbiome.Understanding how antibiotic-resistant bacteria are transmitted to humans through meat and plant foods is important when considering public health, food safety, and the subsequent economic burden. “We found differences in the ability of bacteria to silently colonize the gut after ingestion, depending on a variety of host and bacterial factors. We mimicked antibiotic and antacid treatments, as both could affect the ability of superbugs to survive passage from the stomach to the intestines.Marlène Maeusli Related StoriesAntibiotic combination effective against drug-resistant PseudomonasAntibiotic susceptibility pattern of Enterobacteriaceae found in GhanaMultifaceted intervention for acute respiratory infection improves antibiotic-prescribingOne of the antibiotics tested in the study did not make the superbug better able to hide itself in the mouse intestines, but a second antibiotic led to stable gut colonization after ingestion. Colonization was also altered after the E. coli bacteria was consumed with food, along with consuming an antacid before ingesting the E. coli.In a separate study also presented at the annual meeting of the American Society for Microbiology, six probiotic Bacillus strains were found to be resistant to several types of antibiotics.With Bacillus strains often being used in probiotic products purporting to benefit the health of the gut, researcher and Masters student at CSU Fresno Emmanuel Flores felt it was important to determine whether “probiotic Bacillus are capable of transferring their own antibiotic resistance to bacteria and cause illness such as food poisoning.”Fresno’s study found that probiotic Bacillus does have the potential to transfer antibiotic resistance, but further tests are required to discover which types of bacteria this resistance can be transferred to.Marlène Maeusli explained the future steps in the investigations into plant foods and their role in transmitting superbugs to animals and humans. She said: “We continue to seek the plant characteristics and host factors that result in key microbial community shifts in the gut that put us at risk for colonization and those that prevent it. The environment and human health – in this context via agriculture and microbiomes – are inextricably linked.” Sources: Plants – Not Just Antibiotic-Fed Poultry and Livestock – May be Transmitting Superbugs to People. ASM Press Release. June 22, 2019. Antibiotic Resistance in Spore-Forming Probiotic Bacteria. ASM Press Release. June 21, 2019. Monika Wisniewska / ShutterstockThe Centers for Disease Control and Prevention estimated that agriculture was responsible for 20% of the 2 million infections that are resistant to antibiotics that occur every year. While this estimate is based on infections and superbugs (so called because of their resistance to antibiotics) caused by the consumption of meat, there is a paucity of research into how big an impact plants have in transmitting these superbugs to humans.In a mouse study conducted by the USC researchers, it was discovered that superbugs were able to “hide” in the mice’s intestines after they had been fed lettuce contaminated with E. coli, an antibiotic-resistant bacteria.The researchers accurately mimicked the nature of a superbug infection caused by plants, which does not cause immediate symptoms or signs of illness. The bacteria causing superbug outbreaks can live inside the intestines for up to several years, only causing infection (like urinary infections, for example) when they travel outside of the intestines.After infecting lettuce with E. coli and feeding it to the mice, their fecal samples were analyzed over time.Lead author of the study Marlène Maeusli, PhD candidate at Keck School of Medicine at the University of Southern California, said: “Our findings highlight the importance of tackling foodborne antibiotic-resistance from a complete food chain perspective that includes plant-foods in addition to meat.”
In this Wednesday, Dec. 20, 2017, file photo, a clerk reaches to a shelf to pick an item for a customer order at the Amazon Prime warehouse, in New York. Amazon announced Thursday, Jan. 18, 2018, that it has narrowed down its potential site for a second headquarters in North America to 20 metropolitan areas, mainly on the East Coast. (AP Photo/Mark Lennihan, File) Maybe next time: Cities see failed Amazon bids as trial runs ___DETROIT”We would have loved to have made it into the next round for Amazon’s second headquarters but everyone here is incredibly proud of the proposal we submitted,” Mayor Mike Duggan said. “It showed a clear vision for the future of our city and brought out the very best of our city and our region.”___MEMPHIS, Tennessee”We came together and gave it our best shot,” Mayor Jim Strickland said. “The good news is that this exercise showed us new ways to showcase our city that we are already using to attract other businesses.””Memphis has momentum and other companies have seen and will continue to see our value”The city offered Amazon $60 million in cash incentives.___KANSAS CITY, Missouri”I can understand that some Kansas Citians may be disappointed, but it’s important to remember that as a result of this very collaborative effort, more people today know more great things about Kansas City than they ever did before,” said Mayor Sly James. “Kansas City will continue to develop transformational projects and partnerships that continue the momentum you feel in every block and every neighborhood of this great city. We truly are a city on the rise, and I look forward to our exciting future.”___DELAWAREDelaware’s Gov. John Carney and the state’s congressional delegation said they were “of course” disappointed not to be chosen.”But we used this opportunity to showcase all the options in Delaware not just for Amazon, but for any business looking for a location to set down roots and grow,” they said. “In that respect, Delaware’s effort—which brought together leaders in the public and private sectors to promote our great state—was a resounding success. Going forward, we’ll do everything we can to support Philadelphia’s application, to help bring Amazon to our region.”___NEW HAMPSHIRE”New Hampshire’s groundbreaking proposal to recruit Amazon was the most comprehensive business marketing plan our state has ever produced,” Gov. Chris Sununu said in a statement. “While we always knew that our bid was considered a long shot, we are excited that it is already serving as a template for other businesses that now have New Hampshire on their radar. Our commitment to economic and workforce development is already yielding results. We will never stop emphasizing that New Hampshire is open for business, open for workers, and open for opportunity.” Amazon’s move to whittle its list for a second headquarters leaves more than 200 municipalities disappointed. Here are statements from some of the places that didn’t make the tech giant’s cut to 20 contenders: Explore further Citation: Amazon’s potential HQ2 sites leaves many cities disappointed (2018, January 19) retrieved 18 July 2019 from https://phys.org/news/2018-01-amazon-potential-hq2-sites-cities.html New Hampshire’s Amazon proposal was centered in Londonderry and emphasized the state’s lack of a sales or income tax.___SAN DIEGO”While disappointed San Diego/Chula Vista did not advance, we are not at all surprised,” said Mark Cafferty, president and CEO of the San Diego Regional Economic Development Corp. “We knew that this would be a long shot based on geography and incentive options, but we also know that as a region, San Diego can most definitely compete with others in terms of talent, entrepreneurship, innovation and quality of life.”___NORTHERN CALIFORNIAThe two bids submitted by cities in the San Francisco Bay Area were both rejected by Amazon. Bay Area Council President Jim Wunderman said the decision was disappointing. “We’re not completely surprised by Amazon’s decision,” he said. “The Bay Area is one of the most innovative regions in the world and the huge economic expansion we have witnessed here over the past 10 years has created significant challenges in the form of high housing costs, high cost of living and growing traffic. We are working hard to address these challenges, but we suspect they factored heavily in Amazon’s decision to look elsewhere.”___VIRGINIA BEACH, VIRGINIA”We’re disappointed the City of Virginia Beach was not listed among the top 20 finalists for this project. However, we’re excited the Commonwealth of Virginia is still under consideration,” Virginia Beach Mayor William Sessoms Jr. said. “A project of this magnitude will create many opportunities, and, if Virginia is selected, we expect Virginia Beach and Hampton Roads will benefit.” This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. © 2018 The Associated Press. All rights reserved.
Citation: Nintendo says working with Tencent to release Switch in China (2019, April 26) retrieved 17 July 2019 from https://phys.org/news/2019-04-nintendo-tencent-china.html Nintendo says full-year profit up nearly 40% on strong game sales © 2019 AFP Explore further Japanese games giant Nintendo said Friday it was working with Chinese internet firm Tencent to roll out its popular Switch console in China, confirming rumours that have dramatically pushed up its share price. Mario from Super Mario Bros. is already a well-known character “Nintendo… is announcing that a collaboration is in progress with Tencent Holdings Limited… to release the Nintendo Switch video game system in China,” the firm said in a brief statement.The announcement came a day after Nintendo unveiled strong full-year profit numbers lifted by strong sales of blockbuster game titles for the Switch console.Net profit for the fiscal year to March rose 39.0 percent from a year earlier to 194 billion yen ($1.7 billion), on sales of 1.2 trillion yen, up 13.7 percent.It said then that sales of Switch hardware were projected to rise six percent to 18 million units for the current fiscal year with plans to release “Super Mario Maker 2”, “Pokemon Sword and Pokemon Shield” and “The Legend of Zelda”.The Switch has become a huge global seller, helped by the release of innovative, family-friendly titles that have wowed critics and gamers alike.The company’s shares have surged more than 12 percent since news reports said earlier this month that its games and the Switch would soon be available in China via Tencent.Nintendo boss Shuntaro Furukawa was quoted as saying on Thursday that they wanted to grow China into a major market like Japan, the US, and Europe.”But the size of the game console market is small. So it might not be easy,” said Furukawa.’Definitely positive news’However, Nintendo stock was off three percent in early exchanges on Friday, as analysts said they had been hoping for news of a new Switch console.The Tencent news is “definitely positive news”, said Hideki Yasuda, an analyst at Ace Research Institute in Tokyo. “Shares are down because people wanted to square positions before the holidays.”After the closing bell on Friday, Japan will embark on an unprecedented 10-day holiday as special days off to celebrate the emperor’s abdication combine with the traditional “Golden Week” break.The long holiday has sparked some fears that Japanese markets will be volatile when they reopen as traders catch up with the news that has broken during that period.The Switch has “enormous potential” to succeed in China, Yasuda said, partly due to the games’ family-friendly nature.”Chinese authorities have strict rules when it comes to consumer products… you cannot show running blood and corpses.”Nintendo’s games in general avoid grotesque depictions. I feel it should face an easier time than others when it applies for permits,” the analyst told AFP.The characters such as Mario are already well recognised, which should also give it an edge.And although most Chinese gamers play on PCs, Nintendo’s software “offers benefits that PCs don’t”, said Yasuda.”You can carry it around. You can hook it to TVs. It offers various styles of gaming. It has already been accepted around the world,” he noted. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
May 06, 2019 COMMENTS Prime Minister Narendra Modi is to visit Cyclone Fani hit Odisha on May 6 to take stock of the situation in the state. The Prime Minister spoke to Odisha Chief Minister Naveen Patnaik on Saturday and announced his plans to visit the storm-hit state on Twitter. In the fifth of the seven phases of General Elections 2019 to be held on May 6, a total of 51 seats across seven states will go to polls. Voting will take place in a number of seats in Uttar Pradesh, Rajasthan, Madhya Pradesh, West Bengal, Bihar, Jharkhand and Jammu and Kashmir. Both Rae Bareli and Amethi — represented by Sonia Gandhi and Rahul Gandhi respectively — will witness a heated contest between Congress and BJP heavy weights.US Commerce Secretary Wilbur Ross is to meet Commerce Minister Suresh Prabhu on Monday to discuss trade-related issues amid America’s decision to withdraw export benefits to Indian exporters. Issues such as withdrawal of GSP benefits by Washington are expected to come up for the discussion. The US decided to withdraw export benefits to Indian exporters under the Generalized System of Preferences programme, which is expected to impact India’s exports to the US worth $5.6 billion under this scheme. The Supreme Court is to to hear on May 6 a plea of an AIADMK MLA, V. T. Kalaiselvan, who has been served a notice by the Tamil Nadu assembly Speaker for indulging in “anti-party activities” under the anti-defection law. A bench of Chief Justice Ranjan Gogoi and Justice Deepak Gupta said it will hear the plea on Monday. Senior advocate Kapil Sibal, appearing for Kalaiselvan, said the Speaker has served him a notice under the anti-defection law and the matter requires urgent hearing as he will disqualify him for alleged anti-party activities.INS Ranjit, the frontline missile destroyer of the Indian Navy, is to be decommissioned on Monday. INS Ranjit, the third of the five Kashin-class destroyers built by the erstwhile USSR, was commissioned in 1983. The ship will be decommissioned at the Naval Dockyard, Visakhapatnam. The ceremony will be attended by personnel who have served on-board INS Ranjit in the past and will also include officers and sailors from the commissioning crew. SHARE SHARE EMAIL Prime Minister Narendra Modi addresses an election rally for the forthcoming 2019 Lok Sabha elections. – PTI SHARE Published on COMMENT
Health economist Tomas Philipson has been named acting chairman of the White House Council of Economic Advisers, a White House spokesman said Monday. Mr. Philipson, a professor at the University of Chicago, has served as one of three members of the council since August 2017. He has been serving as the acting chairman after the resignation of Kevin Hassett on June 28. Mr….