By Lois Zoppi, BAJun 25 2019Researchers from the University of Southern California (USC) at the annual meeting of the American Society for Microbiology have revealed that plant foods may be transmitting antibiotic resistance to the gut microbiome.Understanding how antibiotic-resistant bacteria are transmitted to humans through meat and plant foods is important when considering public health, food safety, and the subsequent economic burden. “We found differences in the ability of bacteria to silently colonize the gut after ingestion, depending on a variety of host and bacterial factors. We mimicked antibiotic and antacid treatments, as both could affect the ability of superbugs to survive passage from the stomach to the intestines.Marlène Maeusli Related StoriesAntibiotic combination effective against drug-resistant PseudomonasAntibiotic susceptibility pattern of Enterobacteriaceae found in GhanaMultifaceted intervention for acute respiratory infection improves antibiotic-prescribingOne of the antibiotics tested in the study did not make the superbug better able to hide itself in the mouse intestines, but a second antibiotic led to stable gut colonization after ingestion. Colonization was also altered after the E. coli bacteria was consumed with food, along with consuming an antacid before ingesting the E. coli.In a separate study also presented at the annual meeting of the American Society for Microbiology, six probiotic Bacillus strains were found to be resistant to several types of antibiotics.With Bacillus strains often being used in probiotic products purporting to benefit the health of the gut, researcher and Masters student at CSU Fresno Emmanuel Flores felt it was important to determine whether “probiotic Bacillus are capable of transferring their own antibiotic resistance to bacteria and cause illness such as food poisoning.”Fresno’s study found that probiotic Bacillus does have the potential to transfer antibiotic resistance, but further tests are required to discover which types of bacteria this resistance can be transferred to.Marlène Maeusli explained the future steps in the investigations into plant foods and their role in transmitting superbugs to animals and humans. She said: “We continue to seek the plant characteristics and host factors that result in key microbial community shifts in the gut that put us at risk for colonization and those that prevent it. The environment and human health – in this context via agriculture and microbiomes – are inextricably linked.” Sources: Plants – Not Just Antibiotic-Fed Poultry and Livestock – May be Transmitting Superbugs to People. ASM Press Release. June 22, 2019. Antibiotic Resistance in Spore-Forming Probiotic Bacteria. ASM Press Release. June 21, 2019. Monika Wisniewska / ShutterstockThe Centers for Disease Control and Prevention estimated that agriculture was responsible for 20% of the 2 million infections that are resistant to antibiotics that occur every year. While this estimate is based on infections and superbugs (so called because of their resistance to antibiotics) caused by the consumption of meat, there is a paucity of research into how big an impact plants have in transmitting these superbugs to humans.In a mouse study conducted by the USC researchers, it was discovered that superbugs were able to “hide” in the mice’s intestines after they had been fed lettuce contaminated with E. coli, an antibiotic-resistant bacteria.The researchers accurately mimicked the nature of a superbug infection caused by plants, which does not cause immediate symptoms or signs of illness. The bacteria causing superbug outbreaks can live inside the intestines for up to several years, only causing infection (like urinary infections, for example) when they travel outside of the intestines.After infecting lettuce with E. coli and feeding it to the mice, their fecal samples were analyzed over time.Lead author of the study Marlène Maeusli, PhD candidate at Keck School of Medicine at the University of Southern California, said: “Our findings highlight the importance of tackling foodborne antibiotic-resistance from a complete food chain perspective that includes plant-foods in addition to meat.”
Citation: Nintendo says working with Tencent to release Switch in China (2019, April 26) retrieved 17 July 2019 from https://phys.org/news/2019-04-nintendo-tencent-china.html Nintendo says full-year profit up nearly 40% on strong game sales © 2019 AFP Explore further Japanese games giant Nintendo said Friday it was working with Chinese internet firm Tencent to roll out its popular Switch console in China, confirming rumours that have dramatically pushed up its share price. Mario from Super Mario Bros. is already a well-known character “Nintendo… is announcing that a collaboration is in progress with Tencent Holdings Limited… to release the Nintendo Switch video game system in China,” the firm said in a brief statement.The announcement came a day after Nintendo unveiled strong full-year profit numbers lifted by strong sales of blockbuster game titles for the Switch console.Net profit for the fiscal year to March rose 39.0 percent from a year earlier to 194 billion yen ($1.7 billion), on sales of 1.2 trillion yen, up 13.7 percent.It said then that sales of Switch hardware were projected to rise six percent to 18 million units for the current fiscal year with plans to release “Super Mario Maker 2”, “Pokemon Sword and Pokemon Shield” and “The Legend of Zelda”.The Switch has become a huge global seller, helped by the release of innovative, family-friendly titles that have wowed critics and gamers alike.The company’s shares have surged more than 12 percent since news reports said earlier this month that its games and the Switch would soon be available in China via Tencent.Nintendo boss Shuntaro Furukawa was quoted as saying on Thursday that they wanted to grow China into a major market like Japan, the US, and Europe.”But the size of the game console market is small. So it might not be easy,” said Furukawa.’Definitely positive news’However, Nintendo stock was off three percent in early exchanges on Friday, as analysts said they had been hoping for news of a new Switch console.The Tencent news is “definitely positive news”, said Hideki Yasuda, an analyst at Ace Research Institute in Tokyo. “Shares are down because people wanted to square positions before the holidays.”After the closing bell on Friday, Japan will embark on an unprecedented 10-day holiday as special days off to celebrate the emperor’s abdication combine with the traditional “Golden Week” break.The long holiday has sparked some fears that Japanese markets will be volatile when they reopen as traders catch up with the news that has broken during that period.The Switch has “enormous potential” to succeed in China, Yasuda said, partly due to the games’ family-friendly nature.”Chinese authorities have strict rules when it comes to consumer products… you cannot show running blood and corpses.”Nintendo’s games in general avoid grotesque depictions. I feel it should face an easier time than others when it applies for permits,” the analyst told AFP.The characters such as Mario are already well recognised, which should also give it an edge.And although most Chinese gamers play on PCs, Nintendo’s software “offers benefits that PCs don’t”, said Yasuda.”You can carry it around. You can hook it to TVs. It offers various styles of gaming. It has already been accepted around the world,” he noted. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
Next Mumbai: Unable to locate 3-year-old Divyansh who fell into gutter, search teams call off operationsThe search for a three-year-old boy who fell into an open stormwater drain here on Wednesday has been stopped, a civic official said on Friday night.advertisement Press Trust of India MumbaiJuly 12, 2019UPDATED: July 12, 2019 23:06 IST Divyansh Singh, who fell into a drain at Ambedkar Chowk in Malad East around 10 pm Wednesday, remained untraceable even after 48 hours.The search for a three-year-old boy who fell into an open stormwater drain here on Wednesday has been stopped, a civic official said on Friday night.Divyansh Singh, who fell into a drain at Ambedkar Chowk in Malad East around 10 pm Wednesday, remained untraceable even after 48 hours.The search was finally stopped around 10 pm, the spokesperson of the Brihanmumbai Municipal Corporation (BMC) said.The search team covered over 10 km of drainage line but in vain, another official said.The team of 50 BMC, Fire Brigade and National Disaster Response Force personnel searched the drain line by opening all manholes along the stretch.The child’s fall into the drain near Goregaon-Mulund Link Road was captured by CCTV cameras.Divyansh’s father Suraj Bhan Singh had alleged earlier that the authorities were not doing enough to trace his son.”The BMC, fire brigade and NDRF are not showing any intent to find my son. The fire brigade team did not even have a torch. NDRF jawans came and went back after marking their presence. Our family wanted to protest but were stopped by the police,” Singh had claimed.He also hit out at Mumbai Mayor Vishwanath Mahadeshwar for not bothering to meet him or other members of the family.ALSO READ | 20 hours on, no trace of Mumbai toddler who fell down gutter, family inconsolableALSO WATCH | 2-year-old falls into open drain in MumbaiFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byAnupriya Thakur Tags :Follow Mumbai